The Link Between Inflammation and Cancer : Wounds that do not heal / edited by Angus G. Dalgleish, Burkhard Haefner

Von:

Dalgleish, Angus G [aut]

Mitwirkende(r):

Haefner, Burkhard [oth]

Resource type: Ressourcentyp: Buch (Online)Buch (Online)Sprache: Englisch Reihen: Cancer Treatment and Research ; 130 | SpringerLink BücherVerlag: Boston, MA : Springer Science+Business Media, Inc, 2006Beschreibung: Online-Ressource (XII, 254 p, digital)ISBN:

9780387262833

Schlagwörter:

Andere physische Formen: 9780387262826 | Buchausg. u.d.T.: 9780387262826 DDC-Klassifikation:

616.994
610
610

RVK: RVK: XH 4920LOC-Klassifikation:

RC254-282
RC268.5

NLM-Klassifikation:

QZ 202

DOI: DOI: 10.1007/b137303Online-Ressourcen:

Zusammenfassung: The transcription factor NF-kB has long been known to play a central role in the immune system by regulating the expression of key genes. Moreover, activation of this transcription factor helps a wide variety of cell types survive damage induced by pro-apoptotic stimuli. Owing to its critical role in the regulation of pro-inflammatory genes, NF-kB has long been regarded as a promising target for the discovery of anti-inflammatory drugs. More recently, NF-kB has emerged as a major culprit in a variety of human cancers mainly due to its ability to protect transformed cells from apoptosis. This finding should not have come as a surprise since there exists a link between inflammation and cancer which was already suggested by Galen and later demonstrated by Virchow. This link, of crucial importance for the design of novel strategies for cancer treatment, is the topic of this book.PPN: PPN: 1646581334Package identifier: Produktsigel: ZDB-1-SMI | ZDB-2-SME

Exemplare ( 0 )

Dieser Titel hat keine Exemplare