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The Serotonin Receptors : From Molecular Pharmacology to Human Therapeutics / edited by Kim A. Neve, Bryan L. Roth

Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: The Receptors | SpringerLink BücherPublisher: Totowa, NJ : Humana Press Inc, 2006Description: Online-Ressource (digital)ISBN:
  • 9781597450805
Subject(s): Genre/Form: Additional physical formats: 9781588295682 | Buchausg. u.d.T.: The serotonin receptors. Totowa, NJ : Humana Press, 2006. XVII, 618 S.DDC classification:
  • 615.1
  • 612.8/042
RVK: RVK: WW 4120 | XI 6500 | VS 7900 | WD 5832LOC classification:
  • RS1-441
  • QP801.S4
NLM classification:
  • QV 126
DOI: DOI: 10.1007/978-1-59745-080-5Online resources: Summary: A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.PPN: PPN: 1647353580Package identifier: Produktsigel: ZDB-1-SMI | ZDB-2-SME
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