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Stem Cells And Myocardial Regeneration / edited by Marc S. Penn
Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Contemporary Cardiology | SpringerLink BücherPublisher: Totowa, NJ : Humana Press Inc, 2007Description: Online-RessourceISBN:- 9781597452724
- 616.1/24060724
- 616.124060724
- QH588.S83
- WG 280
Contents:
Summary: Stem Cells and Myocardial Regeneration is a comprehensive bench to bedside examination of stem cell-based therapies for cardiac dysfunction. The contributors, all leading researchers in their area of expertise, explore recent advances in the laboratory and in clinical trials. This volume emphasizes the near epidemic status of chronic heart failure (CHF) in the United States and abroad, and evaluates the level of success and failure of current optimal medical therapy. Specific attention is also given to both the basic cell types and pathways involved in cardiac stem cell research and the clinical issues that surround it. Parts I and II of Stem Cells and Myocardial Regeneration examine various cardiac stem cell types, including hematopoietic, mesenchymal, and endogenous cells and critical physiological pathways, including chemokines, stem cell differentiation, and arrhythmia mechanisms. Part III focuses on clinical issues intrinsic to delivery of stem cells to the heart at the time of myocardial infarction (MI) and in patients with CHF. Part IV contains up-to-date reviews and analyses of the findings of stem cell-based clinical trials of acute MI and CHF. The concluding section presents a summary of cardiac stem cell research and outlines potential obstacles to future study.PPN: PPN: 1649003269Package identifier: Produktsigel: ZDB-1-SMI | ZDB-2-SME
Front Matter; The Challenge for Stem Cell Therapy; Hematopoietic Stem Cells for Myocardial Regeneration; Mesenchymal Stem Cells for Cardiac Therapy; Multipotent Adult Progenitor Cells; Mesenchymal Progenitor Cells for Vascular Network Formation and Cardiac Muscle Regeneration; Umbilical Cord Blood Stem Cells for Myocardial Regeneration and Angiogenesis; Endogenous Cardiac Stem Cells; Embryonic Stem Cells for Myocardial Repair; Chemokine and Homing Factor Expression in Acute Myocardial Infarction and Chronic Heart Failure; Stem Cell Differentiation Toward a Cardiac Myocyte Phenotype
Electrical Coupling and/or Ventricular Tachycardia Risk of Cell TherapyCell Therapy for Myocardial Damage; Aspects of Percutaneous Cellular Cardiomyoplasty; Stem Cells and Myocardial Regeneration; Measures of Effective Cell-Based Therapy; Whole Bone Marrow Transplantation; Clinical Angioblast Therapy; Use of Skeletal Myoblasts for the Treatment of Chronic Heart Failure; Bone Marrow and Angioblast Transplantation; Strategies for Cytokine Modification and Stem Cell Mobilization for Acute Myocardial Infarction; Summary and Future Challenges; Back Matter
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