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RNA and DNA Diagnostics / edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski

Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: RNA Technologies | SpringerLink BücherPublisher: Cham ; s.l. : Springer International Publishing, 2015Description: Online-Ressource (X, 349 p. 124 illus., 78 illus. in color, online resource)ISBN:
  • 9783319173054
Subject(s): Additional physical formats: 9783319173047 | Erscheint auch als: RNA and DNA diagnostics. Druck-Ausgabe. Cham : Springer, 2015. X, 349 S.DDC classification:
  • 611.01816
  • 599.935
LOC classification:
  • RB155-155.8 QH431
  • RB155-155.8
  • QH431
DOI: DOI: 10.1007/978-3-319-17305-4Online resources:
Contents:
Electrochemical Biosensors for miRNA DetectionElectrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems -- DNA for Non-Nucleic Acid Sensing -- Aptamers in Oncotherapy -- Genotyping of Single Nucleotide Polymorphism -- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA -- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics -- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures -- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods -- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics -- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices -- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics -- Detection and Assessment of microRNA Expression in Human Disease.
Summary: The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman’s famous statement “What I cannot create, I do not understand.”PPN: PPN: 165734410XPackage identifier: Produktsigel: ZDB-2-SBL
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