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Computational Methods for Processing and Analysis of Biological Pathways / by Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos

By: Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: SpringerBriefs in Computer Science | SpringerLink Bücher | Springer eBook Collection Computer SciencePublisher: Cham : Springer, 2017Description: Online-Ressource (VIII, 87 p. 11 illus. in color, online resource)ISBN:
  • 9783319538686
Subject(s): Additional physical formats: 9783319538679 | Druckausg.: Computational methods for processing and analysis of biological pathways. Cham : Springer, 2017. viii, 87 Seiten | Printed edition: 9783319538679 LOC classification:
  • QH324.2-324.25
DOI: DOI: 10.1007/978-3-319-53868-6Online resources: Summary: This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathwaysSummary: Introduction -- Networks and Pathways in Systems Pharmacology -- Time Varying Methods for Pathway and Sub-Pathway Analysis -- Identification of Differentially Expressed Pathways and Sub-PathwaysPPN: PPN: 1657567249Package identifier: Produktsigel: ZDB-2-SCS
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