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Mechanism of Functional Expression of the Molecular Machines / by Masahiro Kinoshita

By: Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: SpringerBriefs in Molecular Science | SpringerLink BücherPublisher: Singapore ; s.l. : Springer Singapore, 2016Description: Online-Ressource (X, 70 p. 30 illus., 24 illus. in color, online resource)ISBN:
  • 9789811014864
Subject(s): Additional physical formats: 9789811014840 | Ersch. auch als: Mechanism of functional expression of the molecular machines. Druck-Ausgabe Singapore : Springer, 2016. x, 70 SeitenLOC classification:
  • QD450-882
DOI: DOI: 10.1007/978-981-10-1486-4Online resources: Summary: Introduction -- Importance of Translational, Configurational Entropy of Water -- Molecular Machines -- Concluding Remarks: Mechanism of Functional Expression Common in the Molecular Machines.Summary: This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system.PPN: PPN: 1657643050Package identifier: Produktsigel: ZDB-2-SEB | ZDB-2-SXC | ZDB-2-CMS
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