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The biological chemistry of Nickel / edited by Deborah Zamble (University of Toronto, Canada Email: deborah.zamble@utoronto.ca), Magdalena Rowińska-Żyrek (University of Wroclaw, Poland Email: magdalena.rowinska-zyrek@chem.uni.wroc.pl) and Henryk Kozłowski (University of Wroclaw, Poland Email: henrykoz@wchuwr.chem.uni.wroc.pl)

Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: ISSN | RSC metallobiology series ; no. 10Publisher: Cambridge : Royal Society of Chemistry, [2017]Description: 1 Online-RessourceISBN:
  • 9781788010580
  • 9781788011235
Subject(s): Additional physical formats: 9781782624981 | Erscheint auch als: The biological chemistry of nickel. Druck-Ausgabe. London : Royal Society of Chemistry, 2017. xv, 380 SeitenDDC classification:
  • 572.52625
RVK: RVK: WD 4750Online resources: Summary: An essential text for biochemists, biologists and medicinal chemists, this book provides a comprehensive review of the latest findings in nickel biology, covering the function, biochemistry, toxicology and medical applications of nickel systems.Summary: Cover -- The Biological Chemistry of Nickel -- Preface -- Contents -- Chapter 1 - Introduction to the Biological Chemistry of Nickel -- 1.1 Nickel Utilization -- 1.1.1 Nickel in Biology -- 1.1.2 Nickel in Humans -- 1.2 Nickel Enzymes -- 1.3 Nickel Availability and Distribution -- 1.4 Applications -- 1.5 Outstanding Questions -- Acknowledgements -- References -- Chapter 2 - Oceanic Nickel Biogeochemistry and the Evolution of Nickel Use -- 2.1 Introduction -- 2.2 Nickel Geochemistry in Modern Oceans -- 2.2.1 Modern Oceanic Nickel Chemical Speciation, Sources and Sinks -- 2.2.2 Seawater Depth Profiles -- 2.2.3 Correlations with Other Elements -- 2.3 Modern Marine Microbial Nickel Enzyme Usage and Geochemical Signatures -- 2.3.1 The Oxic Surface Ocean -- 2.3.1.1 NiSOD -- 2.3.1.2 Urease -- 2.3.1.3 Nickel's Role in Nitrogen Fixation -- 2.3.1.4 Imaging Nickel in Phytoplankton -- 2.3.2 The Deep Ocean -- 2.3.3 Anoxic Sediments and Seafloor Seeps -- 2.4 Microbial Growth Response to Varying Nickel Concentrations -- 2.5 Evolutionary Implications of Changes in Oceanic Nickel over Geologic Time -- Acknowledgements -- References -- Chapter 3 - Nickel Toxicity and Carcinogenesis -- 3.1 Introduction -- 3.1.1 Toxicology -- 3.1.2 Epigenetics -- 3.1.3 Nickel Exposure -- 3.2 Nickel Carcinogenesis -- 3.2.1 Human, Animal, and In vitro Investigations -- 3.2.2 Nickel's Effect on the DNA Methylome -- 3.2.3 Nickel's Effect on Post-Translational Histone Modifications -- 3.2.4 Nickel's Effect on microRNA Expression -- 3.3 Conclusions -- Acknowledgements -- References -- Chapter 4 - Nickel Binding Sites - Coordination Modes and Thermodynamics -- 4.1 Coordination Chemistry of Nickel. Why and for Whom Did Nature Choose It -- 4.2 Nickel Complexes with Peptides Containing Amino Acid Residues with Non-Coordinating Side Chains.PPN: PPN: 1657849066Package identifier: Produktsigel: ZDB-30-PQE
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