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High-Performance Computational Solutions in Protein Bioinformatics / by Dariusz Mrozek

By: Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: SpringerBriefs in Computer Science | SpringerLink BücherPublisher: Cham ; s.l. : Springer International Publishing, 2014Description: Online-Ressource (XIX, 109 p. 56 illus., 21 illus. in color, online resource)ISBN:
  • 9783319069715
Subject(s): Additional physical formats: 9783319069708 | Erscheint auch als: High-performance computational solutions in protein bioinformatics. Druck-Ausgabe Cham : Springer, 2014. XIX, 109 S.DDC classification:
  • 570.285
RVK: RVK: WC 7700LOC classification:
  • QH324.2-324.25
DOI: DOI: 10.1007/978-3-319-06971-5Online resources:
Contents:
Formal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular ModelingMultithreaded PSS-SQL for Searching Databases of Secondary Structures -- GPU and CUDA for 3D Protein Structure Similarity Searching -- Cloud Computing for 3D Protein Structure Alignment -- General Discussion and Concluding Remarks.
Summary: Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels, and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics, and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databasesPPN: PPN: 1658605551Package identifier: Produktsigel: ZDB-2-SCS
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