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Current Advances in Osteosarcoma / edited by Eugenie S. Kleinerman, M.D.
Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Advances in Experimental Medicine and Biology ; 804 | SpringerLink BücherPublisher: Cham ; s.l. : Springer International Publishing, 2014Description: Online-Ressource (XII, 359 p. 65 illus., 54 illus. in color, online resource)ISBN:- 9783319048437
- RC261-271
Contents:
Summary: Current Advances in Osteosarcoma summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in this field over the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and is the most common histological form of bone cancer. Osteosarcoma accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat. In order to improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. This volume will provide a comprehensive review of these new discoveries in one singular text, which will help move the field forwardPPN: PPN: 1658623215Package identifier: Produktsigel: ZDB-2-SBL
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