Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy : New Perspectives and Opportunities / edited by Christopher D. Gregory

Contributor(s):

Gregory, Christopher D [Hrsg.]

Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Advances in Experimental Medicine and Biology ; 930 | SpringerLink BücherPublisher: Cham ; s.l. : Springer International Publishing, 2016Description: Online-Ressource (XVII, 247 p. 29 illus., 28 illus. in color, online resource)ISBN:

9783319394060

Subject(s):

Additional physical formats: 9783319394046 | Druckausg.: Apoptosis in cancer pathogenesis and anti-cancer therapy. Switzerland : Springer, 2016. xvii, 247 SeitenRVK: RVK: VS 9102LOC classification:

RC261-271

NLM classification:

QU 375

DOI: DOI: 10.1007/978-3-319-39406-0Online resources:

Summary: Foreword -- Preface -- 1. Molecular Cell Biology of Apoptosis and Necroptosis in Cancer -- 2. Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis -- 3. Micro-environmental Effects of Cell Death in Malignant Disease -- 4. Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis -- 5. Axl and Mer Receptor Tyrosine Kinases: Distinct and Non-overlapping Roles in Inflammation and Cancer? -- 6. Immunogenic Apoptotic Cell Death and Anti-cancer Immunity -- 7. Cancer Cell Death-inducing Radiotherapy - Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity -- 8. Novel Approaches to Apoptosis-inducing Therapies -- 9. Killing Is Not Enough - How Apoptosis Hijacks Tumor-associated Macrophages to Promote Cancer Progression -- IndexSummary: This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alikePPN: PPN: 1658662555Package identifier: Produktsigel: ZDB-2-SBL

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