Ras Superfamily Small G Proteins: Biology and Mechanisms 2 : Transport / edited by Alfred Wittinghofer

By:

Wittinghofer, Alfred, 1943- [aut]

Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: SpringerLink BücherPublisher: Cham ; s.l. : Springer International Publishing, 2014Description: Online-Ressource (VI, 298 p. 35 illus. in color, online resource)ISBN:

9783319077611

Subject(s):

Additional physical formats: 9783319077604 | Erscheint auch als: Ras superfamily small G proteins ; 2: Transport. Druck-Ausgabe. Cham : Springer, 2014. VI, 298 S.DDC classification:

571.6
570
572.643 23

RVK: RVK: WE 5240LOC classification:

QH573-671

DOI: DOI: 10.1007/978-3-319-07761-1Online resources:

Contents:

Prenylation of RabGTPases, their delivery to membranes and Rab recyclingRab proteins and the organization of organelle membrane domains -- Effectors of Rab GTPases: Rab binding specificity and their role in coordination of Rab function and localization -- A Rab effector called the exocyst and related vesicle tether complexes -- RabGEFs and GAPs - the enigma variations -- Ran in Nucleocytoplasmic Transport -- Ran in Mitosis -- Arf proteins and their regulators: at the interface between membrane lipids and the protein trafficking machinery -- Small G Proteins: Arf family GTPases in vesicular transport -- ARF-LIKE (ARL) Proteins -- GTPase-Activating Proteins for the Arf-family Small GTPases: not only for the termination -- Rag GTPases.

Summary: This second of two volumes discusses subfamily proteins involved in nucleo-cytoplasmic and vesicular transport mechanisms inside the cell. In this volume, the focus lies on the Rab, Ran and Arf subfamily members. Like Volume 1, the book was written by internationally renowned scientists in the field of small G-proteins. The biochemistry, structure, function and G-protein/effector interactions are described in detailed reviews. Together with Volume 1, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It was written for graduates and professors in biochemistry and cell biology interested in the mechanism and function of small G-proteins, but also offers an extremely valuable resource for those readers who are new to the fieldPPN: PPN: 1659248124Package identifier: Produktsigel: ZDB-2-SBL

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