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The chemical biology of phosphorus / by Christopher T. Walsh

By: Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Chemical biology ; 13Publisher: Cambridge : Royal Society of Chemistry, [2021]Copyright date: © 2021Description: 1 Online-Ressource (xix, 546 Seiten)ISBN:
  • 9781839162312
  • 9781839162329
Subject(s): Additional physical formats: 9781839162022 | Erscheint auch als: The chemical biology of phosphorus. Druck-Ausgabe Cambridge : Royal Society of Chemistry, 2021. xix, 546 SeitenDDC classification:
  • 572.553
RVK: RVK: WD 4750LOC classification:
  • QD181.P1
  • MLCM 2025/42837 (Q)
DOI: DOI: 10.1039/9781839162312Online resources: Summary: Introduction to Phosphorus Chemical Biology; Inorganic Phosphate, Pyrophosphate and Polyphosphate; ATP as the Premier Biologic Phosphoryl Transfer Reagent; Nucleotidyl Transfers (ATPs and NTPs); Pyrophosphoryl and Adenosyl Transfers from Mg-ATP; Activated Phosphoryl Groups and Biosynthetic Paths to ATP; Phosphomonoesters: Enzymatic Formation and Decomposition; Phosphodiesters and Phosphotriesters; Phosphorylases: Inorganic Phosphate as Oxygen Nucleophile; N-P Bond Chemical Biology; C-P Bonds in Biology: Phosphonates and Phosphinates; P-S Bonds: Phosphorothioates; Scope and Roles of Posttranslational Protein Phosphorylations; Noncanonical Phosphoproteomes; Canonical Phosphoproteomics: Phosphoserine, Phosphothreonine and Phosphotyrosine; Noncanonical Phosphoproteomics II; Broad Biologic Arcs from Only Four Types of Phosphate MoleculesSummary: Alexander Todd, the 1957 Nobel laureate in chemistry is credited with the statement: where there is life, there is phosphorus. Phosphorus chemical biology underlies most of life's reactions and processes, from the covalent bonds that hold RNA and DNA together, to the making and spending 75 kg of ATP every day, required to run almost all metabolic and mechanical events in cells. Authored by a renowned biochemist, The Chemical Biology of Phosphorus provides an in-depth, unifying chemical approach to the logic and reactivity of inorganic phosphate and its three major derivatives (anhydrides, mono- and diesters) throughout biology to examine why life depends on phosphorus. Covering the breadth of phosphorus chemistry in biology, this book is ideal for biochemistry students, postgraduates and researchers interested in the chemical logic of phosphate metabolites, energy generation, biopolymer accumulation and phosphoproteomicsPPN: PPN: 1738958558Package identifier: Produktsigel: ZDB-1-RSEK
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