Custom cover image
Custom cover image

MicroRNAs: Novel Biomarkers and Therapeutic Targets for Human Cancers

By: Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Publisher: [Erscheinungsort nicht ermittelbar] : MDPI - Multidisciplinary Digital Publishing Institute, 2018Description: 1 Online-Ressource (272 p.)ISBN:
  • 9783038972525
  • 9783038972532
Subject(s): Online resources: Summary: MicroRNAs (miRNAs) constitute a large family of small, approximately 20–22-nucleotide, non-coding RNAs that are involved in gene regulation, mainly at the post-transcriptional level. Multiple lines of evidence have indicated that miRNAs play important roles in the maintenance of biological homeostasis and that aberrant expression levels of miRNAs are involved in the onset of many diseases, including cancer. In various types of cancer, miRNAs play important roles in tumor initiation and development. Recently, miRNAs have been demonstrated to also be secreted via small endosome-derived vesicles called exosomes—which are derived from multiple cell types—including immunocytes and cancer cells. Exosomal miRNAs exert important functions in cell-to-cell communication and have been investigated as prognostic and diagnostic biomarkersPPN: PPN: 1778525032Package identifier: Produktsigel: ZDB-94-OAB
No physical items for this record

Open Access. Unrestricted online access star

Creative Commons https://creativecommons.org/licenses/by-nc-nd/4.0 cc

English

KIT – The University in the Helmholtz Association                         Home | Impressum | Datenschutz | Barrierefreiheit | KIT