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The three functional states of proteins : structured, intrinsically disordered, and phase separated / edited by Timir Tripathi, Molecular and Structural Biophysics Laboratory, Department of Zoology, School of Life Sciences, North-Eastern Hill University, Shillong, Meghalaya, India, Vladimir N. Uversky, Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States
Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Publisher: London, United Kingdom ; San Diego, CA : Academic Press, [2025]Copyright date: ©2025Description: 1 Online-Ressource (xvii, 456 pages) : illustrations (chiefly colorISBN:- 9780443218101
- 0443218102
- 0443218099
- 9780443218095
- QP551
Contents:
PPN: PPN: 1940673178Package identifier: Produktsigel: BSZ-4-NLEBK-KAUB | ZDB-4-NLEBK
The three functional states of proteins : beyond the classical "lock and key" paradigm / Timir Tripathi and Vladimir N. Uversky -- Ordered proteins and structure-function relationship : a classical view / Munishwar Nath Gupta, Timir Tripathi and Vladimir N. Uversky -- Binding of a substrate ("lock and key") and conformational adaptation ("induced fit") are different stages of enzyme action / Munishwar Nath Gupta, Timir Tripathi and Vladimir N. Uversky -- Intrinsically disordered proteins : functionality of chaos / Aakanksha Singh [and 3 others] -- Protein conformation-based phenotypic switching and implications in the origin and evolution of multicellularity / Sourabh Kotnala [and 9 others] -- Hybrid proteins : fusion chimeras and natural wonders / Muhamed Adilović [and 4 others] -- Functional protein oligomers / Subhashree Sahoo [and 5 others] -- Fuzzy complexes / Julien Mignon, Tanguy Leyder and Catherine Michaux -- SMARTQ : single-molecule amyloid fibril tracking and quantification : a method for accurately imaging, tracking, and quantifying the growth of individual amyloid fibrils using TIRF / William P. Olsen [and 3 others] -- Structural polymorphism in amyloids : states within proteins' solid-state / Shailendra Dhakal and Vijayaraghavan Rangachari -- Liquid-liquid phase separation, biomolecular condensates, and membraneless organelles : a novel blueprint of intracellular organization / Sushma Subedi, Vladimir N. Uversky and Timir Tripathi -- Physical principles and molecular interactions underlying protein phase separation / Sushma Subedi [and 3 others] -- Various levels of phase transitions in the protein universe and around / Alexei V. Finkelstein and Vladimir N. Uversky -- Targeting phase separated protein states for drug discovery / Niharika Nag [and 3 others] -- Protein hydrogels : structure, characteristics, and applications / Altijana Hromić-Jahjefendić, Maryam Golzardi and Vladimir N. Uversky -- Interactions among the three protein states / Pavel Kadeřávek, Karel Kubíček and Lukáš Žídek -- Frustration and fuzziness in the three functional states of proteins / Priyanka Dogra and Bappaditya Chandra -- Thermoresponsive intrinsically disordered protein polymers / Vladimir N. Uversky, Timir Tripathy and Orkid Coskuner-Weber -- The evolution and exploration of intrinsically disordered and phase-separated protein states / Chi Fung Willis Chow and Agnes Toth-Petroczy -- Computational modeling of intrinsically disordered and phase-separated protein states / Orkid Coskuner-Weber and Vladimir N. Uversky -- Molecular dynamics simulations of intrinsically disordered proteins, fuzzy complexes, and phase-separated protein states / Xubo Lin -- Biological complexity of the phase-separated protein states / Kundlik Gadhave [and 3 others] -- Protein structure-function continuum / Timir Tripathi and Vladimir N. Uversky.
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