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What's wrong with my mouse? : behavioral phenotyping of transgenic and knockout mice / Jacqueline N. Crawley

By: Resource type: Ressourcentyp: BuchBookLanguage: English Publisher: Hoboken, NJ : Wiley, c 2007Edition: 2. edDescription: XVI, 523 S. : Ill., graph. DarstISBN:
  • 9780471471929
Subject(s): Additional physical formats: Erscheint auch als: What's wrong with my mouse?. Online-Ausgabe 2nd ed. Hoboken, NJ : Wiley, 2007. XVI, 523 S.DDC classification:
  • 573.8
  • 599.3
  • 591.5
  • 573.8/480724 22
  • 573.8419353
RVK: RVK: WG 3450LOC classification:
  • QP356.22
NLM classification:
  • 2007 E-383
  • QY 60.R6
Contents:
Designer mice : scope and sourcebooks -- Of unicorns and chimeras : how to generate a transgenic or knockout mouse for behavioral phenotyping -- General health : give your mouse a physical -- Motor functions : open field, holeboard, rotarod, balance, grip, circadian activity, circling, stereotypy, ataxic gait, seizures -- Sensory abilities : olfaction, vision, hearing, taste, touch, nociception -- Learning and memory : Morris swim task, spatial mazes, cued and contextual conditioning, conditioned taste aversion, conditioned eyeblink, olfactory discrimination, social recognition, passive avoidance, schedule controlled operant tasks, motor learning, attention -- Feeding and drinking : daily consumption, restricted access, choice tests, microstructural analysis -- Reproductive behaviors : sexual and parental behaviors -- Social behaviors : social interaction, nesting, grooming, juvenile play, aggression -- Emotional behaviors : animal models of psychiatric disorders : mouse models of fear, anxiety, depression, schizophrenia -- Reward : self-administration of addictive drugs, conditioned place preference -- Neurodevelopment and neurodegeneration : assaying behaviours in infant, juvenile, and aged mice -- Putting it all together : choice of tests, order of testing, number of mice, equipment, housing and testing environment -- The next generation : conditional and inducible mutations, viral vector gene delivery, RNA silencing, quantitative trait loci analysis, DNA microarrays, chemical mutagenesis, gene therapy, ethical issues
Call number: Grundsignatur: 2007 E 1477(2)PPN: PPN: 518856895
Holdings
Item type Home library Collection Shelving location Call number Status Barcode
Freihandbestand ausleihbar Bibliothek Campus Süd biol 6.8 Lesesaal Naturwissenschaften (LSN) 2007 E 1477(2) Available 49363492090
Total holds: 0