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Statistical issues in drug development / Stephen Senn

By: Resource type: Ressourcentyp: BuchBookLanguage: English Series: Statistics in practicePublisher: Chichester ; Hoboken, NJ : Wiley, 2007Edition: 2. edDescription: XIX, 498 S. : graph. Darst. ; cmISBN:
  • 9780470018774
Subject(s): DDC classification:
  • 615.190727
  • 615/.190727
MSC: MSC: *62P10 | 62-01 | 92C50RVK: RVK: QH 252LOC classification:
  • RM301.25
NLM classification:
  • QV 771
Contents:
Action note:
  • 2
Summary: A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --Summary: The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --Summary: Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related mattersCall number: Grundsignatur: 2008 A 1356(2)PPN: PPN: 537924094
Holdings
Item type Home library Collection Shelving location Call number Status Barcode
Freihandbestand Präsenznutzung Fachbibliothek Chemie phar 4.4 Bibliothek / frei aufgestellt 2008 A 1356(2) Not for loan 49250336090
Total holds: 0

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