Statistical issues in drug development / Stephen Senn

Von:

Senn, Stephen, 1953- [aut]

Resource type: Ressourcentyp: BuchBuchSprache: Englisch Reihen: Statistics in practiceVerlag: Chichester ; Hoboken, NJ : Wiley, 2007Auflage: 2. edBeschreibung: XIX, 498 S. : graph. Darst. ; cmISBN:

9780470018774

Schlagwörter:

DDC-Klassifikation:

615.190727
615/.190727

MSC: MSC: *62P10 | 62-01 | 92C50RVK: RVK: QH 252LOC-Klassifikation:

RM301.25

NLM-Klassifikation:

QV 771

Inhalte:

Bearbeitungsvermerk:

Zusammenfassung: A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --Zusammenfassung: The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --Zusammenfassung: Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related mattersCall number: Grundsignatur: 2008 A 1356(2)PPN: PPN: 537924094

Exemplare ( 1 )
Titelinformationen ( 1 )

Exemplare
Medientyp	Heimatbibliothek	Sammlung	Standort	Signatur	Status	Barcode
Freihandbestand Präsenznutzung	Fachbibliothek Chemie	phar 4.4	Bibliothek / frei aufgestellt	2008 A 1356(2)	Nicht ausleihbar	49250336090

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