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Calcium binding proteins / Eugene Permyakov and Robert H. Kretsinger

By: Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Wiley series in protein and peptide science ; 5 | Wiley Series in Protein and Peptide Science Ser ; v.15Publisher: Hoboken, N.J : Wiley, 2010Edition: Online-AusgDescription: Online-Ressource (1 online resource (xi, 573 p., [12] p. of plates)) : ill. (some col.)ISBN:
  • 9781283025010
  • 1283025019
  • 9780470872383
Subject(s): Additional physical formats: 9780470525845. | 128302909X | 9780470525845 | Erscheint auch als: Calcium binding proteins. Druck-Ausgabe Hoboken, New Jersey : Wiley, 2011. IX, 573 S.DDC classification:
  • 572.69
  • 572/.69 22
  • 572
LOC classification:
  • QP552.C24
Online resources: Summary: An up-to-date exploration on the latest developments in all the major families of calcium binding proteins Playing a prominent role as a signal transducer, calcium is an important participant in the communication pipeline directing cellular activity. This expert guide explains the unique and highly diverse functions of calcium in biology, culminating with a discussion of the calcium binding proteins that act as secondary messengers in cells and are responsible in controlling vital bodily mechanisms such as muscle contraction and the regulation of enzymes. A comprehensive volume reflecting breakthrough science, Calcium Binding Proteins: Contains current information on all major families of calcium binding proteins including their structural, physico-chemical and functional properties, as well as their evolution Discusses techniques that underlie the description of proteins, including NMR, circular dichroism, optical rotatory dispersion spectroscopy, calorimetry, and crystallography Describes the structures, physical characteristics, functions, and general patterns in the evolution of calcium binding proteins This book relies on the most current biological findings to cover the patterns of biochemical phenomena such as calcium homeostasis, min-eralization, and cell signaling involving specific proteins. Summarizing ongoing studies and presenting general hypotheses that help to focus future research, Calcium Binding Proteins provides newcomers to this field as well as established professionals with a conceptual framework instru-mental in advancing their scientific pursuits.Summary: Intro -- CALCIUM BINDING PROTEINS -- CONTENTS -- Preface -- 1 Historical Perspective -- 1.1 Biomineralization -- 1.2 Coagulation -- 1.3 Secondary Messengers (Anticipated) -- 1.4 Colloids -- 1.5 Cross-Linking and Cell Surfaces -- 1.6 Secondary Messengers (Updated) -- 1.7 Pumps, Channels, and Ionophores -- 1.8 Calcium Binding Proteins -- 1.9 Secondary Messengers (Yet Again) -- 1.10 Mitochondria -- 1.11 Pumps, Channels, and Ionophores -- 1.12 Hormones -- 1.13 Measurement -- 1.14 Biomineralization: Redux -- 2 Physiological Processes Involving Calcium Binding Proteins -- 2.1 Calcium as a Secondary Messenger -- 2.2 Calcium Buffers -- 2.3 Calcium Pumps and Channels -- 2.4 Mitochondria -- 2.5 Eubacteria -- 2.6 Calcium and Extracellular Proteins -- 2.7 Biomineralization -- 2.8 Calcium and Viruses -- 3 Comparison of the Ca2+ Ion with Other Metal Cations -- 3.1 Calcium Isotopes -- 3.2 Calcium in the Environment -- 3.3 Uses of Calcium -- 3.4 Health Effects of Calcium -- 3.5 Biologically Significant Metals in the Periodic Table -- 3.6 Hydration of Metal Ions -- 3.7 "Hard" and "Soft" Metal Ions -- 4 Complexes of Calcium and Other Cations with Compounds of Low Molecular Weight -- 4.1 Crystal Structures of Complexes of Calcium with Low Molecular Weight Compounds -- 4.2 Dissociation Constants of Calcium and Analogs with Small Compounds -- 4.3 Solubilities of Calcium and Analogs with Small Compounds -- 5 Stoichiometry, Kinetics, and Thermodynamics of Calcium Binding -- 5.1 Stoichiometry, Affinity, and Cooperativity of Binding -- 5.2 Kinetics of Binding -- 5.3 Partition of Free Energy of Binding (G) Among Enthalpy (H) and Entropy (S) -- 6 Experimental Methods Used to Study Calcium Binding to Proteins -- 6.1 Radioactivity -- 6.2 Ion-Selective Electrodes -- 6.3 Calcium Buffers -- 6.4 Dialysis, Equilibrium, and Flow -- 6.5 Proteolysis -- 6.6 Deuterium Exchange.PPN: PPN: 809244896Package identifier: Produktsigel: ZDB-26-MYL | ZDB-30-PAD | ZDB-30-PQE
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