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Extremophiles : sustainable resources and biotechnological implications / edited by Om V. Singh

Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Publisher: Hoboken, NJ : Wiley-Blackwell, c2013Edition: Online-AusgDescription: Online-Ressource (1 online resource (xxiii, 429 p.)) : ill. (some col.)ISBN:
  • 9781283705462
  • 128370546X
  • 9781118394120
Subject(s): Additional physical formats: 9781118394120 | 9781118103005. | 1283705427 | Erscheint auch als: Extremophiles. Druck-Ausgabe. Hoboken, NJ : Wiley-Blackwell, 2013. XXIII, 429 S.DDC classification:
  • 578.758
  • 578.75/8 23
RVK: RVK: WF 5850LOC classification:
  • QR100.9
Online resources: Summary: Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articles by expert scientists who shed light on broad-ranging areas of progress in the development of smart therapeutics for multiple disease types and products for industrial use. It bridges technological gaps, focusing on critical aspects of extremolytes and the mechanisms regulating their biosynthesis that are relevant to human health and bioenergy, including value-added products of commercial significance as well as other potentially viable products. This groundbreaking guide: Introduces the variety of extremophiles and their extremolytes including extremozymes Provides an overview of the methodologies used to acquire extremophiles Reviews the literature on the diversity of extremophiles Offers tools and criteria for data interpretation of various extremolytes/extremozymes Discusses experimental design problems associated with extremophiles and their therapeutic implications Explores the challenges and possibilities of developing extremolytes for commercial purposes Explains the FDA's regulations on certain microbial bio-products that will be of interest to potential industrialists Extremophiles is an immensely useful resource for graduate students and researchers in biotechnology, clinical biotechnology, microbiology, and applied microbiology.Summary: Intro -- EXTREMOPHILES -- Contents -- Contributors -- Introduction -- 1 MOLECULAR EVOLUTION OF EXTREMOPHILES -- 1.1 Introduction -- 1.2 Molecular Evolution of Thermophiles -- 1.2.1 Habitat -- 1.2.2 Cellular Organization -- 1.2.3 Genome -- 1.2.4 Proteome -- 1.3 Molecular Evolution of Psychrophiles -- 1.3.1 Habitat -- 1.3.2 Cellular Organization -- 1.3.3 Genome -- 1.3.4 Proteome -- 1.4 Molecular Evolution of Halophiles -- 1.4.1 Habitat -- 1.4.2 Cellular Organization -- 1.4.3 Genome -- 1.4.4 Proteome -- 1.5 Molecular Evolution of Alkaliphiles -- 1.5.1 Habitat -- 1.5.2 Cellular Organization -- 1.5.3 Genome -- 1.5.4 Proteome -- 1.6 Molecular Evolution of Acidophiles -- 1.6.1 Habitat -- 1.6.2 Cellular Organization -- 1.6.3 Genome -- 1.6.4 Proteome -- 1.7 Molecular Evolution of Barophiles -- 1.7.1 Habitat -- 1.7.2 Cellular Organization -- 1.7.3 Genome -- 1.7.4 Proteome -- 1.8 Engineering Extremophiles -- 1.8.1 Microbiology -- 1.8.2 Molecular Biology -- 1.8.3 Bioinformatics -- 1.9 Case Studies -- 1.9.1 Biofuel Production -- 1.9.2 Bioremediation -- 1.9.3 Pesticide Biodegradation -- 1.9.4 Escherichia coli: A Candidate Extremophile -- 1.9.5 Oil-Spill-Cleaning Bacteria -- 1.9.6 Potential Applications and Benefits -- 1.10 Implications of Engineered Extremophiles on Ecology, Environment, and Health -- 1.11 Conclusions and Recommendations -- References -- 2 ATTAINING EXTREMOPHILES AND EXTREMOLYTES: METHODOLOGIES AND LIMITATIONS -- 2.1 Introduction -- 2.2 Extremophiles: Types and Diversity -- 2.2.1 Thermophiles -- 2.2.2 Psychrophiles -- 2.2.3 Halophiles -- 2.2.4 Alkaliphiles -- 2.2.5 Acidophiles -- 2.2.6 Barophiles -- 2.3 Extremolytes -- 2.3.1 Production and Purification of Extremolytes -- 2.3.2 Detection, Identification, and Quantification of Extremolytes -- 2.3.3 Limitations -- 2.4 Conclusions -- References.PPN: PPN: 809977389Package identifier: Produktsigel: ZDB-26-MYL | ZDB-30-PAD | ZDB-30-PQE
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