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Impedimetric biosensors for medical applications : current progress and challenges / Jo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner

By: Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Publisher number: 860243Language: English Series: Biomedical & nanomedical technologies concise monograph seriesPublisher: New York, New York (ASME, Three Park Avenue. New York, NY 10016) : American Society Of Mechanical Engineers, [2013]Description: Online-Ressource (1 PDF (70 pages)) : illustrationsISBN:
  • 0791860248
  • 9780791860243
Subject(s): Additional physical formats: 0791860248 | 9780791860243 | Erscheint auch als: No title Druck-AusgabeDDC classification:
  • 610.28 23
LOC classification:
  • R857.B54
NLM classification:
  • 2014 D-837
  • QT 36.4
DOI: DOI: 10.1115/1.860243Online resources: Additional physical formats: Also available in print.
Contents:
Summary: In this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors. Read lessPPN: PPN: 816864500Package identifier: Produktsigel: ZDB-240-ASM
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