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Protein kinase inhibitors in research and medicine / ed. by Kevan M. Shokat
Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Methods in enzymology ; 548Publisher: Amsterdam ; Heidelberg [u.a.] : Academic Press, 2014Edition: 1. edDescription: Online Ressource (xii, 241 S., [42] Taf.) : IllISBN:- 9780123979186
- QP606.P76 QP601
- QP601
- QP606.P76
- QU 143
- W1 ME9615K
Contents:
Summary: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad kinome profiling of kinase inhibitors, and designing drug-resistant kinase alleles. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization scienceContains sections focusing on protein kinase inhibitors in research and medicinePPN: PPN: 827063164Package identifier: Produktsigel: ZDB-33-BGM | ZDB-33-EBS | ZDB-33-ESD
Catalytic mechanisms and regulation of protein kinases / Zhihong Wang and Philip A. Cole
A structural atlas of kinases inhibited by clinically approved drugs / Qi Wang, Julie A. Zorn, and John Kuriyan
Fragment-based approaches to the discovery of kinase inhibitors / Paul N. Mortenson, Valerio Berdini, and Marc O'Reilly
Targeting protein kinases with selective and semipromiscuous covalent inhibitors / Rand M. Miller and Jack Taunton
The resistance tetrad : amino acid hotspots for kinome-wide exploitation of drug-resistant protein kinase alleles / Fiona P. Bailey, Veselin I. Andreev, and Patrick A. Eyers
FLiK : a direct-binding assay for the identification and kinetic characterization of stabilizers of inactive kinase conformations / Jeffrey R. Simar and Daniel Rauh
Discovery of allosteric Bcr-Abl inhibitors from phenotypic screen to clinical candidate / Nathanael S. Gray and Doriano Fabbro
The logic and design of analog-sensitive kinases and their small molecule inhibitors / Michael S. Lopez, Joseph I. Kliegman, and Kevan M. Shokat.
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