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Introduction to quantitative cell biology / Wallace F. Marshall (Director, Center for Cellular Construction, Professor, Department of Biochemistry and Biophysics, University of California, San Francisco, CA)

By: Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: Colloquium series on quantitive cell biology ; [# 2]Publisher: [San Rafael, California] : Morgan & Claypool, 2017Copyright date: © 2017Description: 1 Online-Ressource (1 PDF (viii, 49 pages)))ISBN:
  • 1615046690
  • 9781615046690
Subject(s): Additional physical formats: 9781615046683. | Erscheint auch als: 9781615046683 Druck-AusgabeDDC classification:
  • QH583
LOC classification:
  • QH583
NLM classification:
  • QW 541
Online resources: Summary: 2. Quantifying data -- 2.1 Summarizing and visualizing large numbers of examples -- 2.2 Allowing samples to be compared using statistics -- 2.3 Derived quantities -- 2.4 Testing models -- 2.5 Exploratory data analysis -- 2.5.1 Spatial statistics -- 2.5.2 Time series analysis -- 2.6 Machine learning and "big data" -- 2.7 When the numbers, themselves, are directly relevant --Summary: 3. Building and using models -- 3.1 Role of modeling in cell biology -- 3.2 Types of models -- 3.2.1 Ordinary differential equations -- 3.2.2 Partial differential equations -- 3.2.3 Network models -- 3.2.4 Rule-based modeling -- 3.2.5 Agent-based modeling -- 3.2.6 Stochastic modeling -- 3.3 What to do with models once you have them -- 3.3.1 Testing theories -- 3.3.2 Regression and parameter estimation -- 3.3.3 Proofs about extreme behaviors -- 3.3.4 Establishing equivalence with known systems -- 3.3.5 From models to design tools --Summary: 5. Frontiers in quantitative cell biology -- 5.1 New numerical methods -- 5.2 Multiscale modeling of cancer -- 5.3 Measuring and modeling developmental biology --Summary: 6. How to get started in quantitative cell biology -- 6.1 Prerequisites -- 6.2 Resources for learning and teaching -- 6.3 Approaches to interdisciplinary research --Summary: For the past decade or more, much of cell biology research has been focused on determining the key molecules involved in different cellular processes, an analytical problem that has been amenable to biochemical and genetic approaches. Now, we face an integrative problem of understanding how all of these molecules work together to produce living cells, a challenge that requires using quantitative approaches to model the complex interactions within a cell, and testing those models with careful quantitative measurements. This book is an introductory overview of the various approaches, methods, techniques, and models employed in quantitative cell biology, which are reviewed in greater detail in the other volumes in this e-book series. Particular emphasis is placed on the goals and purpose of quantitative analysis and modeling, and the special challenges that cell biology holds for understanding life at the physical levelPPN: PPN: 1003046150Package identifier: Produktsigel: ZDB-4-NLEBK
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