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Gene and Cell Therapy: Biology and Applications / edited by Giridhara R. Jayandharan

Contributor(s): Resource type: Ressourcentyp: Buch (Online)Book (Online)Language: English Series: SpringerLink BücherPublisher: Singapore : Springer Singapore, 2018Description: Online-Ressource (XV, 305 p. 47 illus, online resource)ISBN:
  • 9789811304811
Subject(s): Additional physical formats: 9789811304804 | 9789811304828 | Printed edition: 9789811304804 | Printed edition: 9789811304828 DDC classification:
  • 615.895
LOC classification:
  • RB155.8
NLM classification:
  • QU 560
DOI: DOI: 10.1007/978-981-13-0481-1Online resources: Summary: Recent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeuticsSummary: Chapter 1. Retroviral vectors in gene therapy -- Chapter 2. Adeno-associated virus vectors in gene therapy -- Chapter 3. Nanoparticle-mediated gene delivery -- Chapter 4. Viral/non-viral based hybrid vectors for gene therapy -- Chapter 5. Pharmaco-gene therapy: an alternate perspective -- Chapter 6. Aptamers - Novel molecules in therapeutics -- Chapter 7. Induced pluripotent stem cells -- Chapter 8. Hope or Hype: Stem cells as therapeutics in retinal degenerative diseases -- Chapter 9. Hematopoeitic stem cells: past, present and futurePPN: PPN: 1031836675Package identifier: Produktsigel: ZDB-2-SBL | ZDB-2-SEB | ZDB-2-SXB
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Reproduktion. (Springer eBook Collection. Biomedical and Life Sciences)